Hepatitis B vaccine
- The first dose of a three-dose schedule should be administered at birth, second dose at 6 weeks, and third dose at 6 months (i.e. 0–6 weeks–6 months).
- Administer monovalent hepatitis B vaccine to all newborns within 48 hours of birth.
- Monovalent hepatitis B vaccine should be used for doses administered before age 6
- Administration of a total of 4 doses of hepatitis B vaccine is permissible when a
combination vaccine containing hepatitis B is administered after the birth dose
- Infants who did not receive a birth dose should receive 3 doses of a hepatitis B
containing vaccine starting as soon as feasible.
- The ideal minimum interval between dose 1 and dose 2 is 4 weeks, and between dose 2
and 3 is 8 weeks. Ideally, the final (3rd or 4th) dose in the hepatitis B vaccine series
should be administered no earlier than age 24 weeks and at least 16 weeks after the
first dose, whichever is later.
- Hepatitis B vaccine may also be given in any of the following schedules: Birth, 1 and 6
months, birth, 6 and 14 weeks; 6, 10 and 14 weeks; birth, 6, 10 and 14 weeks, etc.
- All schedules are protective.
- Administer the 3-dose series to those not previously vaccinated.
- In catch-up vaccination, use 0, 1, and 6 months schedule.